Two main complications can derive from incorrect functionality of the hemostatic system: hemorrhage, when the body is not able to timely recover from a blood vessel lesion, and thrombosis, when thrombi are formed that can obstruct blood vessels, causing tissue necrosis.
Those complications can lead to critical outcomes.
Brain hemorrhage and stroke often result in severe consequences, such as death or disability, while venous thrombosis and pulmonary embolism, even though they have a better prognosis, report a higher incidence and need long-term therapies.
Many anticoagulant and antiplatelet drugs have been developed and are used to fight against or prevent thrombosis. However, the effect of these drugs is patient-dependent, therefore monitoring of patients’ conditions with a customized therapeutic approach is essential.